CW July 2004

category image Volume 13
Issue Number 7
July 2004
ISSN 10593802

In CLL, Pretreating Bulky Lymph Nodes Increases Response

Investigators looking to increase remission rates for patients with chronic lymphocytic leukemia (CLL), found that patients with bulky lymph nodes, while least likely to respond to treatment, may respond better if they are pretreated with high dose methylprednisolone (HDMP) or CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone) before consolidation with alemtuzumab (Campath, Berlex).
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Source & Additional Reading

Peter Hillmen, MBChB, PhD, Haematological Malignancy Diagnostic Service, Leeds, UK, in a 40th Annual Meeting of the American Society of Clinical Oncology presentation.

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