CW June 2000

category image Volume 9
Issue Number 6
June 2000
ISSN 10593802

Cytokines in Advanced Melanoma

For almost a decade, various cytokine-based regimens, in various combinations with chemotherapy have been tried in melanoma. Since cytokines are generally regarded as a ?deus ex machina? or cure-all, this is no surprise; however, advanced melanoma is and remains a malignancy which shows a remarkable lack of responsiveness. A number of randomized trials have been recently evaluated.
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Source & Additional Reading

U. Keilholz et al., The emerging role of cytokines in the treatment of advanced melanoma. Oncology 58, 89-95, 2000.
C. Soubrane et al., Interleukin-1b converting enzymes in the metastatic malignant melanoma patients. Proc. Amer. Assoc. Cancer Research 41, 510, 2000.
I. Y. Galaychuk, New approaches for wound healing in melanoma patients. Proc. Amer. Assoc. Cancer Research 41, 511, 2000.
D. M. King et al., Cytokine release by thioguanine-resistant T cell clones from melanoma patients. Proc. Amer. Assoc. Cancer Research 41, 697, 2000.

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