CW March 2000

category image Volume 9
Issue Number 3
March 2000
ISSN 10593802

Electroporation: For Gene Therapy

Plasmid DNA carrying therapeutic genes can be efficiently introduced into tumor cells in animal model by electroporation. Electro-gene therapy can be repeated within short intervals without eliciting antivector cellular immunity that is sometimes observed with viral vectors. Effects of this technique can be improved by combining plasmid injection to the artery feeding the tumor followed by electroporation.
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Source & Additional Reading

Cancer Watch 7, 123, 1998.
Annals of Otology, Rhinology & Laryngology 107, 779, 1998.
T. Nishi et al., Proceedings of the National Academy of Sciences (USA), January 4, 2000.

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