CW January 2003

category image Volume 12
Issue Number 1
January 2003
ISSN 10593802

New Treatment for Invasive Refractory Aspergillosis

Micafungin, a glucan synthesis-inhibitor of the echinocandin structural class, may have potent therapeutic effects for fighting refractory invasive aspergillosis in bone marrow transplant (BMT) patients. Glucan is an essential component of the fungal cell wall. Allogeneic BMT patients with aspergillosis have a poor prognosis, with published success rates for conventional therapy in the 13%-19% range. Standard treatment has been with amphotericin B.
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Source & Addtional Reading

V. Ratanatharathorn, 44th Annual Meeting of the American Society of Hematology.

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