CW April 2001Issue Number 4 April 2001 ISSN 10593802 A New Role for APC Tumor Suppressor GeneMutations in the gene, Adenomatous Polyposis Coli (APC), are responsible for familial colon cancer but also found in the early stages of sporadic colon cancer. Loss of several functions of APC can cause colon cancer. Recent studies demonstrate an additional function for APC, a crucial role during chromosome segregation.
Go to Previous Page Source & Additional Reading K. B. Kaplan et al., Nature Cell Biology, April 2001. Purchase Downloadable Full-text PDF of Article: $10.00 Subscription is more cost effective than purchasing PDFs on-the-fly. Click here for details. Download Complete Issue CW April 2001Purchase Downloadable Full-text PDF of Complete Issue: $10.00 |
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