CW May 2001

category image Volume 10
Issue Number 5
May 2001
ISSN 10593802

Molecular Marker for Early Detection of Breast Cancer in Ductal Fluid

Molecular abnormality develops in a cell long before cancerous cells are identified from morphological changes. If abnormality is detected at this stage, preventive measure could halt the progression of the disease. It has been observed that excess methylation of a critical site on a tumor suppressor gene or other essential genes can prevent its expression of cancer. A very sensitive and specific test has been developed that can assess the degree of methylation in a small number of cells obtained from breast duct fluids.
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Source & Additional Reading

E. Evron et al., The Lancet, April 28.

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